Dynamics of immune reconstitution and activation markers in HIV+ treatment-naïve patients treated with raltegravir, tenofovir disoproxil fumarate and emtricitabine.

The dynamics of CD4+ T cell reconstitution and changes in immune activation and inflammation in HIV-1 disease following initiation of antiretroviral therapy (ART) are incompletely defined and their underlying mechanisms poorly understood.Thirty-nine treatment-naïve patients were treated with raltegr...

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Bibliographic Details
Main Authors: Nicholas T Funderburg, Adriana Andrade, Ellen S Chan, Susan L Rosenkranz, Darlene Lu, Brian Clagett, Heather A Pilch-Cooper, Benigno Rodriguez, Judith Feinberg, Eric Daar, John Mellors, Daniel Kuritzkes, Jeffrey M Jacobson, Michael M Lederman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3867440?pdf=render