Prostate cancer-derived MMP-3 controls intrinsic cell growth and extrinsic angiogenesis

Bone metastatic prostate cancer significantly impacts patient quality of life and overall survival, and despite available therapies, it is presently incurable with an unmet need for improved treatment options. As mediators of tumor progression, matrix metalloproteinases (MMPs) can degrade extracellu...

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Bibliographic Details
Main Authors: Jeremy S. Frieling, Tao Li, Marilena Tauro, Conor C. Lynch
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558620301421