Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells
Summary: Expansion of pulmonary neuroendocrine cells (PNECs) is a pathological feature of many human lung diseases. Human PNECs are inherently difficult to study due to their rarity (<1% of total lung cells) and a lack of established protocols for their isolation. We used induced pluripotent stem...
Main Authors: | Pooja Hor, Vasu Punj, Ben A. Calvert, Alessandra Castaldi, Alyssa J. Miller, Gianni Carraro, Barry R. Stripp, Steven L. Brody, Jason R. Spence, Justin K. Ichida, Amy L. Ryan (Firth), Zea Borok |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2020-05-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004220302686 |
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