Efficient Generation and Transcriptomic Profiling of Human iPSC-Derived Pulmonary Neuroendocrine Cells

Summary: Expansion of pulmonary neuroendocrine cells (PNECs) is a pathological feature of many human lung diseases. Human PNECs are inherently difficult to study due to their rarity (<1% of total lung cells) and a lack of established protocols for their isolation. We used induced pluripotent stem...

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Bibliographic Details
Main Authors: Pooja Hor, Vasu Punj, Ben A. Calvert, Alessandra Castaldi, Alyssa J. Miller, Gianni Carraro, Barry R. Stripp, Steven L. Brody, Jason R. Spence, Justin K. Ichida, Amy L. Ryan (Firth), Zea Borok
Format: Article
Language:English
Published: Elsevier 2020-05-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302686