Evaluating genetic ancestry and self-reported ethnicity in the context of carrier screening

Evaluating genetic ancestry and self-reported ethnicity in the context of carrier screening

Abstract Background Current professional society guidelines recommend genetic carrier screening be offered on the basis of ethnicity, or when using expanded carrier screening panels, they recommend to compute residual risk based on ethnicity. We investigated the reliability of self-reported ethnicit...

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Bibliographic Details
Main Authors: Roman Shraga, Sarah Yarnall, Sonya Elango, Arun Manoharan, Sally Ann Rodriguez, Sara L. Bristow, Neha Kumar, Mohammad Niknazar, David Hoffman, Shahin Ghadir, Rita Vassena, Serena H. Chen, Avner Hershlag, Jamie Grifo, Oscar Puig
Format: Article
Language:English
Published: BMC 2017-11-01
Series:BMC Genetics
Subjects:
Ancestry informative markers
Genetic risk
Carrier screening
Ethnicity
Online Access:http://link.springer.com/article/10.1186/s12863-017-0570-y

Internet

http://link.springer.com/article/10.1186/s12863-017-0570-y

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