Restoration of physiologic loading modulates engineered intervertebral disc structure and function in an in vivo model

Abstract Tissue‐engineered whole disc replacements are an emerging treatment strategy for advanced intervertebral disc degeneration. A challenge facing the translation of tissue‐engineered disc replacement to clinical use are the opposing needs of initial immobilization to advantage integration cont...

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Bibliographic Details
Main Authors: Sarah E. Gullbrand, Dong Hwa Kim, Beth G. Ashinsky, Edward D. Bonnevie, Harvey E. Smith, Robert L. Mauck
Format: Article
Language:English
Published: Wiley 2020-06-01
Series:JOR Spine
Subjects:
Online Access:https://doi.org/10.1002/jsp2.1086