Stimulation of monocytes by placental microparticles involves Toll-like receptors and nuclear factor kappa-light-chain-enhancer of activated B cells

Stimulation of monocytes by placental microparticles involves Toll-like receptors and nuclear factor kappa-light-chain-enhancer of activated B cells

Human pregnancy is accompanied by a mild systemic inflammatory response, which includes the activation of monocytes circulating in maternal blood. This response is exaggerated in preeclampsia, a placental-dependent disorder specific to human pregnancies. We and others showed that placental syncytiot...

Full description

Bibliographic Details
Main Authors: Marianne Simone Joerger-Messerli, Irene eHoesli, Corinne eRusterholz, Olav eLapaire
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-04-01
Series:Frontiers in Immunology
Subjects:
Inflammation
Monocytes
TLR
NF-κB
Human pregnancy
STBM
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00173/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00173/full

Similar Items