Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model

Evaluation of Nanocarrier Targeted Drug Delivery of Capecitabine-PAMAM Dendrimer Complex in a Mice Colorectal Cancer Model

Capecitabine, an effective anticancer drug in colorectal cancer chemotherapy, may create adverse side effects on healthy tissues. In the present study, we first induced colon adenocarcinoma with azoxymethane, a carcinogen agent, and then investigated the potentiality of polyamidoamine (PAMAM) dendr...

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Bibliographic Details
Main Authors: Fatemeh Nabavizadeh, Hafseh Fanaei, Alireza Imani, Jalal Vahedian, Fahimeh Asadi Amoli, Jamal Ghorbi, Hamid Sohanaki, Seyed Mehdi Mohammadi, Ravieh Golchoobian
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2016-09-01
Series:Acta Medica Iranica
Subjects:
Colorectal cancer
Azoxymethane
Capecitabine
Polyamidoamine (PAMAM) dendrimer
Online Access:https://acta.tums.ac.ir/index.php/acta/article/view/5146

Internet

https://acta.tums.ac.ir/index.php/acta/article/view/5146

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