Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and <i>C. elegans</i>

Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and <i>C. elegans</i>

Sirtuin 1 (SIRT1) othologs are ubiquitous NAD<sup>+</sup>-dependent deacetylases that act as nutrient sensors and modulate metabolism and stress responses in diverse organisms. Both mammalian SIRT1 and <i>Caenorhabditis elegans</i> SIR-2.1 have been implicated in dietary rest...

Full description

Bibliographic Details
Main Authors:	Minh Tu Nguyen, Milán Somogyvári, Csaba Sőti
Format:	Article
Language:	English
Published:	MDPI AG 2018-11-01
Series:	International Journal of Molecular Sciences
Subjects:	aging <i>daf-21</i> HDAC stress proteostasis signaling metabolism epigenetics <i>sir-2.1</i>
Online Access:	https://www.mdpi.com/1422-0067/19/11/3661

Similar Items

Metabolites Produced by the Oral Commensal Bacterium <i>Corynebacterium durum</i> Extend the Lifespan of <i>Caenorhabditis elegans</i> via SIR-2.1 Overexpression
by: Jun Hyeong Kim, et al.
Published: (2020-03-01)

Transcriptomic Profiling of DAF-7/TGFβ Pathway Mutants in <i>C. elegans</i>
by: Muhan Hu, et al.
Published: (2020-03-01)

Brevinin-2 Drug Family—New Applied Peptide Candidates Against Methicillin-Resistant <i>Staphylococcus aureus</i> and Their Effects on Lys-7 Expression of Innate Immune Pathway DAF-2/DAF-16 in <i>Caenorhabditis elegans</i>
by: Hui Xie, et al.
Published: (2018-12-01)

Tart Cherry Increases Lifespan in <i>Caenorhabditis elegans</i> by Altering Metabolic Signaling Pathways
by: Shasika Jayarathne, et al.
Published: (2020-05-01)

Never the Two Shall Mix: Robust Indel Markers to Ensure the Fidelity of Two Pivotal and Closely-Related Accessions of <i>Brachypodium distachyon</i>
by: Rhoda A. T. Brew-Appiah, et al.
Published: (2019-06-01)

<i>Glochidion littorale</i> Leaf Extract Exhibits Neuroprotective Effects in <i>Caenorhabditis elegans</i> via DAF-16 Activation
by: Abdel Fawaz Bagoudou, et al.
Published: (2021-06-01)

Extracts of the Tiger Milk Mushroom (<i>Lignosus rhinocerus</i>) Enhance Stress Resistance and Extend Lifespan in <i>Caenorhabditis elegans</i> via the DAF-16/FoxO Signaling Pathway
by: Parinee Kittimongkolsuk, et al.
Published: (2021-01-01)

<i>Bx-daf-22</i> Contributes to Mate Attraction in the Gonochoristic Nematode <i>Bursaphelenchus xylophilus</i>
by: Mengge Gao, et al.
Published: (2019-09-01)

The Role of <i>CASC2</i> and <i>miR-21</i> Interplay in Glioma Malignancy and Patient Outcome
by: Daina Skiriute, et al.
Published: (2020-10-01)

<i>rad21 </i>Is Involved in Corneal Stroma Development by Regulating Neural Crest Migration
by: Bi Ning Zhang, et al.
Published: (2020-10-01)

Knockout of <i>Pi21</i> by CRISPR/Cas9 and iTRAQ-Based Proteomic Analysis of Mutants Revealed New Insights into <i>M. oryzae</i> Resistance in Elite Rice Line
by: Gul Nawaz, et al.
Published: (2020-07-01)

Peer effects and educational achievement: evidence of causal effects using age at school entry as exogenous variation for Peer quality
by: Isabel Pessoa de Arruda Raposo, et al.
Published: (2020-01-01)

Evidence on the marginal impact of a compulsory secondary education reform in Senegal on years of education and changes in high school decisions
by: Michelle S.M. Momo, et al.
Published: (2021-01-01)

SMA-10 Is a Non-Canonical Member of the TGF-β Sma/Mab Pathway and Immunity Regulator via the DAF-2 Insulin Receptor in <i>Caenorhabditis elegans</i>
by: María Pilar de Lucas, et al.
Published: (2021-01-01)

Genome-Wide Identification and Transcriptional Expression of the <i>METTL21C</i> Gene Family in Chicken
by: Ge Yang, et al.
Published: (2019-08-01)

Novel Bioactive Peptides from <i>Meretrix meretrix</i> Protect <i>Caenorhabditis elegans</i> against Free Radical-Induced Oxidative Stress through the Stress Response Factor DAF-16/FOXO
by: Weizhang Jia, et al.
Published: (2018-11-01)

<i>Pantoea</i> <i>agglomerans</i>-Infecting Bacteriophage vB_PagS_AAS21: A Cold-Adapted Virus Representing a Novel Genus within the Family <i>Siphoviridae</i>
by: Monika Šimoliūnienė, et al.
Published: (2020-04-01)

Gender gaps in the path to adulthood for young females and males in six African countries from the 1990s to the 2010s
by: Jane Mariara, et al.
Published: (2018-08-01)

The <i>carB</i> Gene of <i>Escherichia coli</i> BL21(DE3) is Associated with Nematicidal Activity against the Root-Knot Nematode <i>Meloidogyne javanica</i>
by: Yanfei Xia, et al.
Published: (2021-02-01)

Assessment of the In Vivo Antioxidant Activity of an Anthocyanin-Rich Bilberry Extract Using the <i>Caenorhabditis elegans</i> Model
by: Ana M. González-Paramás, et al.
Published: (2020-06-01)

Transcriptomic Analysis of <i>Ficus carica</i> Peels with a Focus on the Key Genes for Anthocyanin Biosynthesis
by: Jing Li, et al.
Published: (2020-02-01)

Expression of the <i>Malus sieversii</i> NF-YB21 Encoded Gene Confers Tolerance to Osmotic Stresses in <i>Arabidopsis thaliana</i>
by: Chen Feng, et al.
Published: (2021-09-01)

Post-Treatment with Erinacine A, a Derived Diterpenoid of <i>H. erinaceus</i>, Attenuates Neurotoxicity in MPTP Model of Parkinson’s Disease
by: Kam-Fai Lee, et al.
Published: (2020-02-01)

Flavonoids’ Effects on <i>Caenorhabditis elegans’</i> Longevity, Fat Accumulation, Stress Resistance and Gene Modulation Involve mTOR, SKN-1 and DAF-16
by: María Alejandra Guerrero-Rubio, et al.
Published: (2021-03-01)

<i>Tbx21</i> and <i>Foxp3</i> Are Epigenetically Stabilized in T-Bet<sup>+</sup> Tregs That Transiently Accumulate in Influenza A Virus-Infected Lungs
by: Yassin Elfaki, et al.
Published: (2021-07-01)

Leucine Supplementation Decreases <i>HDAC4</i> Expression and Nuclear Localization in Skeletal Muscle Fiber of Rats Submitted to Hindlimb Immobilization
by: Paula K. N. Alves, et al.
Published: (2020-12-01)

Bulked Segregant Analysis Coupled with Whole-Genome Sequencing (BSA-Seq) Mapping Identifies a Novel <i>pi21</i> Haplotype Conferring Basal Resistance to Rice Blast Disease
by: Tingmin Liang, et al.
Published: (2020-03-01)

In Silico Structural and Biochemical Functional Analysis of a Novel <i>CYP21A2</i> Pathogenic Variant
by: Michal Cohen, et al.
Published: (2020-08-01)

Identification of the Ovine Keratin-Associated Protein 21-1 Gene and Its Association with Variation in Wool Traits
by: Shaobin Li, et al.
Published: (2019-07-01)

Development and Evaluation of a Novel ELISA for Detection of Antibodies against HTLV-I Using Chimeric Peptides
by: Parvin Mosadeghi, et al.
Published: (2018-04-01)

Mechanisms Protecting <i>Acinetobacter baumannii</i> against Multiple Stresses Triggered by the Host Immune Response, Antibiotics, and outside Host Environment
by: Soroosh Monem, et al.
Published: (2020-07-01)

Synthesis of Some New Folic Acid-Based Heterocycles of Anticipated Biological Activity
by: Ola A. Abu Ali, et al.
Published: (2021-01-01)

The Criminal Law Protection of Personal Property
by: Olga Aleksandrovna Dolgova
Published: (2011-03-01)

Study of the <i>Bacillus thuringiensis</i> Cry1Ia Protein Oligomerization Promoted by Midgut Brush Border Membrane Vesicles of Lepidopteran and Coleopteran Insects, or Cultured Insect Cells
by: Ayda Khorramnejad, et al.
Published: (2020-02-01)

Flexicaulin A, An <i>ent</i>-Kaurane Diterpenoid, Activates p21 and Inhibits the Proliferation of Colorectal Carcinoma Cells through a Non-Apoptotic Mechanism
by: Yixuan Xia, et al.
Published: (2019-04-01)

NAMPT/SIRT2-mediated inhibition of the p53-p21 signaling pathway is indispensable for maintenance and hematopoietic differentiation of human iPS cells
by: Yun Xu, et al.
Published: (2021-02-01)

PtrARF2.1 Is Involved in Regulation of Leaf Development and Lignin Biosynthesis in Poplar Trees
by: Yongyao Fu, et al.
Published: (2019-08-01)

Isolation and Characterization of <i>APETALA3</i> Orthologs and Promoters from the Distylous <i>Fagopyrum esculentum</i>
by: Lingtian Zeng, et al.
Published: (2021-08-01)

The Mean Staple Length of Wool Fibre Is Associated with Variation in the Ovine Keratin-Associated Protein 21-2 Gene
by: Shaobin Li, et al.
Published: (2020-01-01)

Concise Review: Methods and Cell Types Used to Generate Down Syndrome Induced Pluripotent Stem Cells
by: Youssef Hibaoui, et al.
Published: (2015-04-01)

Cannot write session to /tmp/vufind_sessions/sess_imgsb4vg9tmhj6a30dvk7t8kpq