Hsp90 Stabilizes SIRT1 Orthologs in Mammalian Cells and <i>C. elegans</i>

Sirtuin 1 (SIRT1) othologs are ubiquitous NAD<sup>+</sup>-dependent deacetylases that act as nutrient sensors and modulate metabolism and stress responses in diverse organisms. Both mammalian SIRT1 and <i>Caenorhabditis elegans</i> SIR-2.1 have been implicated in dietary rest...

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Bibliographic Details
Main Authors: Minh Tu Nguyen, Milán Somogyvári, Csaba Sőti
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/19/11/3661