PSMA Expression in Glioblastoma as a Basis for Theranostic Approaches: A Retrospective, Correlational Panel Study Including Immunohistochemistry, Clinical Parameters and PET Imaging

PSMA Expression in Glioblastoma as a Basis for Theranostic Approaches: A Retrospective, Correlational Panel Study Including Immunohistochemistry, Clinical Parameters and PET Imaging

AimThe aim of the current study was to enlighten the evolution of prostate-specific membrane antigen (PSMA) expression in glioblastoma between initial diagnosis and recurrence in order to provide preliminary insight for further clinical investigations into innovative PSMA-directed treatment concepts...

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Main Authors: Adrien Holzgreve, Annamaria Biczok, Viktoria C. Ruf, Friederike Liesche-Starnecker, Katja Steiger, Maximilian A. Kirchner, Marcus Unterrainer, Lena Mittlmeier, Jochen Herms, Jürgen Schlegel, Peter Bartenstein, Jörg-Christian Tonn, Nathalie L. Albert, Bogdana Suchorska
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Oncology
Subjects:
glioblastoma (GBM)
glioma
prostate specific membrane antigen (PSMA)
positron emission tomography (PET)
immunohistochemistry (IHC)
theranostic
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.646387/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.646387/full

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