Polygenic risk scoring to assess genetic overlap and protective factors influencing posttraumatic stress, depression, and chronic pain after motor vehicle collision trauma

Abstract Posttraumatic stress (PTS), depressive symptoms (DS), and musculoskeletal pain (MSP) are common sequelae of trauma exposure. Although these adverse posttraumatic neuropsychiatric sequelae (APNS) are often studied separately, clinical comorbidity is high. In a cohort of European American mot...

Full description

Bibliographic Details
Main Authors: Jarred J. Lobo, Samuel A. McLean, Andrew S. Tungate, David A. Peak, Robert A. Swor, Niels K. Rathlev, Phyllis L. Hendry, Sarah D. Linnstaedt
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Translational Psychiatry
Online Access:https://doi.org/10.1038/s41398-021-01486-5