A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in <i>Plasmodium falciparum</i>

A Photoalkylative Fluorogenic Probe of Guttiferone A for Live Cell Imaging and Proteome Labeling in <i>Plasmodium falciparum</i>

Guttiferone A (GA) <b>1</b>, a polycyclic polyprenylated acylphloroglucinol (PPAP) isolated from the plant <i>Symphonia globulifera</i> (Clusiaceae), constitutes a novel hit in antimalarial drug discovery. PPAPs do not possess identified biochemical targets in malarial parasi...

Full description

Bibliographic Details
Main Authors: Romain Duval, Kevin Cottet, Magali Blaud, Anaïs Merckx, Sandrine Houzé, Philippe Grellier, Marie-Christine Lallemand, Sylvie Michel
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Molecules
Subjects:
Guttiferone A
<i>Plasmodium falciparum</i>
7-azidocoumarin
photoactivation
fluorogenesis
Online Access:https://www.mdpi.com/1420-3049/25/21/5139

Internet

https://www.mdpi.com/1420-3049/25/21/5139

Similar Items