The Major Role of NF-κB in the Depth of Invasion on Acral Melanoma by Decreasing CD8 T Cells

The Major Role of NF-κB in the Depth of Invasion on Acral Melanoma by Decreasing CD8 T Cells

Background The tumor microenvironment including immune surveillance affects malignant melanoma (MM) behavior. Nuclear factor κB (NF-κB) stimulates the transcription of various genes in the nucleus and plays a role in the inflammatory process and in tumorigenesis. CD8+ T cells have cytotoxic properti...

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Bibliographic Details
Main Authors: Hermin Aminah Usman, Bethy S. Hernowo, Maringan Diapari Lumban Tobing, Reti Hindritiani
Format: Article
Language:English
Published: Korean Society of Pathologists & the Korean Society for Cytopathology 2018-05-01
Series:Journal of Pathology and Translational Medicine
Subjects:
Acral
CD8 T cells
Invasion
Melanoma
NF-κB
PD-L1
Online Access:http://www.jpatholtm.org/upload/pdf/jptm-2018-04-04.pdf

Internet

http://www.jpatholtm.org/upload/pdf/jptm-2018-04-04.pdf

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