HMGB2 orchestrates mitotic clonal expansion by binding to the promoter of C/EBPβ to facilitate adipogenesis

Abstract High-mobility group box 2 (HMGB2) is an abundant, chromatin-associated protein that plays an essential role in the regulation of transcription, cell proliferation, differentiation, and tumorigenesis. However, the underlying mechanism of HMGB2 in adipogenesis remains poorly known. Here, we p...

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Bibliographic Details
Main Authors: Keren Chen, Junyan Zhang, Feng Liang, Qi Zhu, Shufang Cai, Xian Tong, Zuyong He, Xiaohong Liu, Yaosheng Chen, Delin Mo
Format: Article
Language:English
Published: Nature Publishing Group 2021-07-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03959-3