Effects of hypoxia inducible factor-1α on osteogenic differentiation and angiogenesis related factors of bone marrow mesenchymal stem cells

Effects of hypoxia inducible factor-1α on osteogenic differentiation and angiogenesis related factors of bone marrow mesenchymal stem cells

Objective To investigate the level of hypoxia inducible factor-1α (HIF-1α) on osteoblasts and angiogenesis-associated cytokines in bone marrow mesenchymal stem cells (BMSCs) from SD rats.Methods BMSCs were isolated and cultured and identified by flow cytometry. Plasmid vectors containing upregulated...

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Bibliographic Details
Main Authors: ZUO Xinhui, LI Jun, HAN Xiangzhen, LIU Xiaoyuan, HE Huiyu
Format: Article
Language:zho
Published: Editorial Department of Journal of Prevention and Treatment for Stomatological Diseases 2021-07-01
Series:口腔疾病防治
Subjects:
hypoxia inducible factor-1α ，
bone marrow mesenchymal stem cells，
osteogenic differentiation，
angiogenesis，
runt-related transcription factor 2 ，
platelet derived growth factor-bb，
transforming growth factor-β，
phosphatidylinositol 3-kinase ，
protein kinase b，
bone tissue engineering，
Online Access:http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2021.07.003

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http://www.kqjbfz.com/CN/10.12016/j.issn.2096-1456.2021.07.003

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