Z-Ajoene Inhibits Growth of Colon Cancer by Promotion of CK1α Dependent β-Catenin Phosphorylation

Aberrant activation of a Wnt/β-catenin pathway results in nuclear accumulation of β-catenin in colon cancer. Inhibiting β-catenin is one strategy for treating colon cancer. Here, we identified Z-ajoene, a sulfur containing compound isolated from crushed garlic, as an inhib...

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Bibliographic Details
Main Authors: Hua Li, Ji Hye Jeong, Sung Won Kwon, Sang Kook Lee, Hwa Jin Lee, Jae-Ha Ryu
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/25/3/703