A dynamic interaction between CD19 and the tetraspanin CD81 controls B cell co-receptor trafficking
CD81 and its binding partner CD19 are core subunits of the B cell co-receptor complex. While CD19 belongs to the extensively studied Ig superfamily, CD81 belongs to a poorly understood family of four-pass transmembrane proteins called tetraspanins. Tetraspanins play important physiological roles by...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2020-04-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/52337 |