MicroRNA-34a promoting apoptosis of human lens epithelial cells through down-regulation of B-cell lymphoma-2 and silent information regulator

AIM: To investigate the role of microRNA-34a (miR-34a) in the induction of apoptosis of human lens epithelial (HLE-B3) cells. METHODS: The apoptosis of HLE-B3 cells was detected by Annexin V-PE apoptosis detection kit after the treatment with 200 μmol/L H2O2 for 24h and lentiviral miR-34a vector tr...

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Bibliographic Details
Main Authors: Qing-Lan Li, Hong-Yang Zhang, Yong-Jie Qin, Qian-Li Meng, Xiao-Lei Yao, Hai-Ke Guo
Format: Article
Language:English
Published: Press of International Journal of Ophthalmology (IJO PRESS) 2016-11-01
Series:International Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.cn/en_publish/2016/11/20161104.pdf