Metabolic engineering of Escherichia coli for the synthesis of polyhydroxyalkanoates using acetate as a main carbon source

Abstract Background High production cost of bioplastics polyhydroxyalkanoates (PHA) is a major obstacle to replace traditional petro-based plastics. To address the challenges, strategies towards upstream metabolic engineering and downstream fermentation optimizations have been continuously pursued....

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Bibliographic Details
Main Authors: Jing Chen, Wei Li, Zhao-Zhou Zhang, Tian-Wei Tan, Zheng-Jun Li
Format: Article
Language:English
Published: BMC 2018-07-01
Series:Microbial Cell Factories
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12934-018-0949-0