Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells
Abstract Background We previously reported that mesenchymal stem cells (MSCs) possess therapeutic effects in a murine model of carbon tetrachloride-induced acute liver failure. In the study, we observed that the majority of repopulated hepatocytes were of recipient origin and were adjacent to transp...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
BMC
2017-05-01
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Series: | Stem Cell Research & Therapy |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s13287-017-0560-z |