Exosomes from mesenchymal stem cells induce the conversion of hepatocytes into progenitor oval cells

Abstract Background We previously reported that mesenchymal stem cells (MSCs) possess therapeutic effects in a murine model of carbon tetrachloride-induced acute liver failure. In the study, we observed that the majority of repopulated hepatocytes were of recipient origin and were adjacent to transp...

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Bibliographic Details
Main Authors: Hao-Hsiang Wu, Oscar K. Lee
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Stem Cell Research & Therapy
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13287-017-0560-z