Association of MTOR and AKT Gene Polymorphisms with Susceptibility and Survival of Gastric Cancer.

The phosphoinositide 3-kinase (PI3K)/protein kinase B (PKB, AKT)/mammalian target of rapamycin (mTOR) signaling pathway plays a critical role in angiogenesis and cell growth, proliferation, metabolism, migration, differentiation, and apoptosis. Genetic diversity in key factors of this pathway may in...

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Bibliographic Details
Main Authors: Ying Piao, Ying Li, Qian Xu, Jing-wei Liu, Cheng-zhong Xing, Xiao-dong Xie, Yuan Yuan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4552869?pdf=render