Metabolic engineering of Candida glabrata for diacetyl production.

In this study, Candida glabrata, an efficient pyruvate-producing strain, was metabolically engineered for the production of the food ingredient diacetyl. A diacetyl biosynthetic pathway was reconstructed based on genetic modifications and medium optimization. The former included (i) channeling carbo...

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Bibliographic Details
Main Authors: Xiang Gao, Nan Xu, Shubo Li, Liming Liu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3948628?pdf=render