Vacuolar-type proton ATPase is required for maintenance of apicobasal polarity of embryonic visceral endoderm

Abstract The endocytic compartments keep their interior acidic through the inward flow of protons and anions from the cytosol. Acidification is mediated by a proton pump known as vacuolar-type ATPase (V-ATPase) and transporters conferring anion conductance to the organellar membrane. In this study,...

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Bibliographic Details
Main Authors: Ge-Hong Sun-Wada, Hiroyuki Tabata, Yoh Wada
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-98952-3