Regulating survival and development in the retina: key roles for simple sphingolipids

Many sphingolipids have key functions in the regulation of crucial cellular processes. Ceramide (Cer) and sphingosine (Sph) induce growth arrest and cell death in multiple situations of cellular stress. On the contrary, sphingosine-1-phosphate (S1P), the product of Sph phosphorylation, promotes prol...

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Bibliographic Details
Main Authors: Nora P. Rotstein, Gisela E. Miranda, Carolina E. Abrahan, O. Lorena German
Format: Article
Language:English
Published: Elsevier 2010-06-01
Series:Journal of Lipid Research
Subjects:
eye
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520410004