Functional reinnervation from remaining DA terminals induced by GDNF lentivirus in a rat model of early Parkinson's disease

Glial cell-line derived neurotrophic factor (GDNF) is a good candidate agent for restoring functional reinnervation and/or neuroprotection of dopamine (DA) nigrostriatal system and thus for the treatment of Parkinson's disease (PD). Viral delivery is currently the most likely in vivo strategy f...

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Bibliographic Details
Main Authors: Mara Brizard, Carole Carcenac, Alexis-Pierre Bemelmans, Claude Feuerstein, Jacques Mallet, Marc Savasta
Format: Article
Language:English
Published: Elsevier 2006-01-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996105001919