The neurobiological mechanism underlying hypothalamic GnRH pulse generation: the role of kisspeptin neurons in the arcuate nucleus [version 1; peer review: 4 approved]
This review recounts the origins and development of the concept of the hypothalamic gonadotropin-releasing hormone (GnRH) pulse generator. It starts in the late 1960s when striking rhythmic episodes of luteinizing hormone secretion, as reflected by circulating concentrations of this gonadotropin, we...
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| Format: | Article |
| Language: | English |
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F1000 Research Ltd
2019-06-01
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| Series: | F1000Research |
| Online Access: | https://f1000research.com/articles/8-982/v1 |