Myc, Oncogenic Protein Translation, and the Role of Polyamines
Deregulated protein synthesis is a common feature of cancer cells, with many oncogenic signaling pathways directly augmenting protein translation to support the biomass needs of proliferating tissues. MYC’s ability to drive oncogenesis is a consequence of its essential role as a governor l...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2018-05-01
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Series: | Medical Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/2076-3271/6/2/41 |