Myc, Oncogenic Protein Translation, and the Role of Polyamines

Deregulated protein synthesis is a common feature of cancer cells, with many oncogenic signaling pathways directly augmenting protein translation to support the biomass needs of proliferating tissues. MYC’s ability to drive oncogenesis is a consequence of its essential role as a governor l...

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Bibliographic Details
Main Authors: Andrea T. Flynn, Michael D. Hogarty
Format: Article
Language:English
Published: MDPI AG 2018-05-01
Series:Medical Sciences
Subjects:
MYC
Online Access:http://www.mdpi.com/2076-3271/6/2/41