Analytical Methodologies for the Stereoselective Determination of Sibutramine: An Overview

Sibutramine is a chiral anti-obesity drug which decreases food intake and increases energy expenditure. In therapy it is used as a racemic mixture; however both pharmacokinetic and pharmacodynamic data have revealed enantioselective behavior of sibutramine and its major active metabolites. Several c...

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Bibliographic Details
Main Authors: Vlad Alexandru Robert, Hancu Gabriel, Kelemen Hajnal, Ciurcă Diana, Tero-Vescan Amelia
Format: Article
Language:English
Published: Sciendo 2017-06-01
Series:Acta Medica Marisiensis
Subjects:
Online Access:https://doi.org/10.1515/amma-2017-0021