Theoretical conditions for the coexistence of viral strains with differences in phenotypic traits: a bifurcation analysis

We investigate the dynamics of a wild-type viral strain which generates mutant strains differing in phenotypic properties for infectivity, virulence and mutation rates. We study, by means of a mathematical model and bifurcation analysis, conditions under which the wild-type and mutant viruses, which...

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Bibliographic Details
Main Authors: Anel Nurtay, Matthew G. Hennessy, Josep Sardanyés, Lluís Alsedà, Santiago F. Elena
Format: Article
Language:English
Published: The Royal Society 2019-01-01
Series:Royal Society Open Science
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.181179