Phenylthiourea Binding to Human Tyrosinase-Related Protein 1

Phenylthiourea Binding to Human Tyrosinase-Related Protein 1

Tyrosinase-related protein 1 (TYRP1) is one of the three human melanogenic enzymes involved in the biosynthesis of melanin, a pigment responsible for the color of the skin, hair, and eyes. It shares high sequence identity with tyrosinase, but has two zinc ions in its active site rather than two copp...

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Bibliographic Details
Main Authors: Xuelei Lai, Harry J. Wichers, Montserrat Soler-López, Bauke W. Dijkstra
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:International Journal of Molecular Sciences
Subjects:
human tyrosinase
human tyrosinase-related protein
phenylthiourea
inhibitor
crystal structure
<i>n</i>-glycosylation
albinism
melanogenesis
zinc–copper enzymes
Online Access:https://www.mdpi.com/1422-0067/21/3/915

Internet

https://www.mdpi.com/1422-0067/21/3/915

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