Microarray analysis uncovers a role for Tip60 in nervous system function and general metabolism.

Tip60 is a key histone acetyltransferase (HAT) enzyme that plays a central role in diverse biological processes critical for general cell function; however, the chromatin-mediated cell-type specific developmental pathways that are dependent exclusively upon the HAT activity of Tip60 remain to be exp...

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Bibliographic Details
Main Authors: Meridith Lorbeck, Keerthy Pirooznia, Jessica Sarthi, Xianmin Zhu, Felice Elefant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-04-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3073973?pdf=render