Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics

Chemoenzymatic modular assembly of O-GalNAc glycans for functional glycomics

O-GalNAc glycans are essential in many biological and pathological processes, but difficult to access due to their structural complexity and synthetic challenges. Here, the authors report an efficient chemoenzymatic modular assembly strategy to construct structurally diverse O-GalNAc glycans, use th...

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Bibliographic Details
Main Authors: Shuaishuai Wang, Congcong Chen, Madhusudhan Reddy Gadi, Varma Saikam, Ding Liu, He Zhu, Roni Bollag, Kebin Liu, Xi Chen, Fengshan Wang, Peng George Wang, Peixue Ling, Wanyi Guan, Lei Li
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-23428-x

Internet

https://doi.org/10.1038/s41467-021-23428-x

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