Extracellular enolase of Candida albicans is involved in colonization of mammalian intestinal epithelium

Enolase is secreted by C. albicans and is present in its biofilms although its extracellular function is unknown. Here we show that extracellular enolase mediates the colonization of small intestine mucosa by C. albicans. Assays using intestinal mucosa disks show that C. albicans adhesion is inhibit...

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Bibliographic Details
Main Authors: Richard Cardoso Silva, Ana Carolina Barbosa Padovan, Daniel C Pimenta, Renata Carmona Ferreira, Claudio Vieira Silva, Marcelo R. S. Briones
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcimb.2014.00066/full