Long-Term Survival, Vascular Occlusive Events and Efficacy Biomarkers of First-Line Treatment of CML: A Meta-Analysis

Long-Term Survival, Vascular Occlusive Events and Efficacy Biomarkers of First-Line Treatment of CML: A Meta-Analysis

Large randomized clinical trials and prior meta-analyses indicate that second-generation BCR-ABL tyrosine kinase inhibitors (TKIs) improve surrogate biomarkers in patients with chronic myeloid leukemia (CML) without providing survival benefits. The objective is to evaluate the long-term efficacy and...

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Bibliographic Details
Main Authors: Hélène Haguet, Carlos Graux, François Mullier, Jean-Michel Dogné, Jonathan Douxfils
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cancers
Subjects:
protein kinase inhibitors
overall survival
meta-analysis
leukemia
myelogenous chronic
BCR-ABL positive
Online Access:https://www.mdpi.com/2072-6694/12/5/1242

Internet

https://www.mdpi.com/2072-6694/12/5/1242

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