Synthesis and Antiproliferative Activity of Phosphorus Substituted 4-Cyanooxazolines, 2-Aminocyanooxazolines, 2-Iminocyanooxazolidines and 2-Aminocyanothiazolines by Rearrangement of Cyanoaziridines

Synthesis and Antiproliferative Activity of Phosphorus Substituted 4-Cyanooxazolines, 2-Aminocyanooxazolines, 2-Iminocyanooxazolidines and 2-Aminocyanothiazolines by Rearrangement of Cyanoaziridines

Several phosphorus-substituted <i>N</i>-acylated cyanoaziridines <b>2</b> and <i>N</i>-carbamoylated cyanoziridines <b>5</b> were prepared in good to high yields. <i>N</i>-Acylated cyanoaziridines <b>2</b> were used, after ring...

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Bibliographic Details
Main Authors: Victor Carramiñana, Ana M. Ochoa de Retana, Francisco Palacios, Jesús M. de los Santos
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Molecules
Subjects:
phosphorus substituted cyanoaziridines
4-cyanooxazolines
2-aminocyanooxazolines
2-iminocyanooxazolidines
2-aminocyanothiazolines
antiproliferative effect
Online Access:https://www.mdpi.com/1420-3049/26/14/4265

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https://www.mdpi.com/1420-3049/26/14/4265

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