Perturbation of neuronal cobalamin transport by lysosomal enzyme inhibition
Cbl (cobalamin) utilization as an enzyme cofactor is dependent on its efficient transit through lysosomes to the cytosol and mitochondria. We have previously proposed that pathophysiological perturbations in lysosomal function may inhibit intracellular Cbl transport with consequences for down-strea...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Portland Press, Biochemical Society
2014-01-01
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| Series: | Bioscience Reports |
| Subjects: | |
| Online Access: | http://www.bioscirep.org/bsr/034/e092/bsr034e092.htm |