EZH2 regulates neuroepithelium structure and neuroblast proliferation by repressing p21
The function of EZH2 as a transcription repressor is well characterized. However, its role during vertebrate development is still poorly understood, particularly in neurogenesis. Here, we uncover the role of EZH2 in controlling the integrity of the neural tube and allowing proper progenitor prolifer...
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
The Royal Society
2016-01-01
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Series: | Open Biology |
Subjects: | |
Online Access: | https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150227 |