The impact of senescence-associated T cells on immunosenescence and age-related disorders

Abstract Immunosenescence is age-associated changes in the immunological functions, including diminished acquired immunity against infection, pro-inflammatory traits, and increased risk of autoimmunity. The proportions of memory-phenotype T cells in the peripheral T cell population steadily increase...

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Bibliographic Details
Main Authors: Yuji Fukushima, Nagahiro Minato, Masakazu Hattori
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Inflammation and Regeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41232-018-0082-9