Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies

Background: 20(S)-Protopanaxadiol (20S-PPD) is a fully deglycosylated ginsenoside metabolite and has potent dermal antiaging activity. However, because of its low aqueous solubility and large molecular size, a suitable formulation strategy is required to improve its solubility and skin permeability,...

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Bibliographic Details
Main Authors: Ki-Taek Kim, Min-Hwan Kim, Ju-Hwan Park, Jae-Young Lee, Hyun-Jong Cho, In-Soo Yoon, Dae-Duk Kim
Format: Article
Language:English
Published: Elsevier 2018-10-01
Series:Journal of Ginseng Research
Online Access:http://www.sciencedirect.com/science/article/pii/S122684531730115X