Roles for Non-coding RNAs in Spatial Genome Organization

Genetic loci are non-randomly arranged in the nucleus of the cell. This order, which is important to overall genome expression and stability, is maintained by a growing number of factors including the nuclear envelope, various genetic elements and dedicated protein complexes. Here, we review evidenc...

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Bibliographic Details
Main Authors: Negin Khosraviani, Lauren A. Ostrowski, Karim Mekhail
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fcell.2019.00336/full