Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2

Proteomic and transcriptomic analysis of heart failure due to volume overload in a rat aorto-caval fistula model provides support for new potential therapeutic targets - monoamine oxidase A and transglutaminase 2

<p>Abstract</p> <p>Background</p> <p>Chronic hemodynamic overloading leads to heart failure (HF) due to incompletely understood mechanisms. To gain deeper insight into the molecular pathophysiology of volume overload-induced HF and to identify potential markers and targ...

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Bibliographic Details
Main Authors: Petrak Jiri, Pospisilova Jana, Sedinova Miroslava, Jedelsky Petr, Lorkova Lucie, Vit Ondrej, Kolar Michal, Strnad Hynek, Benes Jan, Sedmera David, Cervenka Ludek, Melenovsky Vojtech
Format: Article
Language:English
Published: BMC 2011-11-01
Series:Proteome Science
Subjects:
Heart failure
hypertrophy
annexins
monoamine oxidase
transglutaminase
Online Access:http://www.proteomesci.com/content/9/1/69

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http://www.proteomesci.com/content/9/1/69

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