Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective

Exploring the Link Between Additive Heritability and Prediction Accuracy From a Ridge Regression Perspective

Genome-Wide Association Studies (GWAS) explain only a small fraction of heritability for most complex human phenotypes. Genomic heritability estimates the variance explained by the SNPs on the whole genome using mixed models and accounts for the many small contributions of SNPs in the explanation of...

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Bibliographic Details
Main Authors: Arthur Frouin, Claire Dandine-Roulland, Morgane Pierre-Jean, Jean-François Deleuze, Christophe Ambroise, Edith Le Floch
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Genetics
Subjects:
heritability
prediction accuracy
ridge regression
mixed model
generalized cross validation
best linear unbiased predictor
Online Access:https://www.frontiersin.org/articles/10.3389/fgene.2020.581594/full

Internet

https://www.frontiersin.org/articles/10.3389/fgene.2020.581594/full

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