Investigation of Ultrasound-Mediated Intracellular Ca<sup>2+</sup> Oscillations in HIT-T15 Pancreatic β-Cell Line

Investigation of Ultrasound-Mediated Intracellular Ca<sup>2+</sup> Oscillations in HIT-T15 Pancreatic β-Cell Line

In glucose-stimulated insulin secretion (GSIS) of pancreatic β-cells, the rise of free cytosolic Ca<sup>2+</sup> concentration through voltage-gated calcium channels (VGCCs) triggers the exocytosis of insulin-containing granules. Recently, mechanically induced insulin secretion pathways...

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Bibliographic Details
Main Authors: Chi Woo Yoon, Nan Sook Lee, Kweon Mo Koo, Sunho Moon, Kyosuk Goo, Hayong Jung, Changhan Yoon, Hae Gyun Lim, K. Kirk Shung
Format: Article
Language:English
Published: MDPI AG 2020-05-01
Series:Cells
Subjects:
ultrasound
calcium oscillations
pancreatic β-cells
purinergic signaling
hemichannels
ATP
Online Access:https://www.mdpi.com/2073-4409/9/5/1129

Internet

https://www.mdpi.com/2073-4409/9/5/1129

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