Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics

Augmentation of Bone Regeneration by Depletion of Stress-Induced Senescent Cells Using Catechin and Senolytics

Despite advances in bone regenerative medicine, the relationship between stress-induced premature senescence (SIPS) in cells and bone regeneration remains largely unknown. Herein, we demonstrated that the implantation of a lipopolysaccharide (LPS) sustained-release gelatin sponge (LS-G) increases th...

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Bibliographic Details
Main Authors: Yoshitomo Honda, Anqi Huang, Tomonari Tanaka, Xiaoyu Han, Beiyuan Gao, Haitao Liu, Xinchen Wang, Jianxin Zhao, Yoshiya Hashimoto, Kazuyo Yamamoto, Naoyuki Matsumoto, Shunsuke Baba, Makoto Umeda
Format: Article
Language:English
Published: MDPI AG 2020-06-01
Series:International Journal of Molecular Sciences
Subjects:
cellular senescence
LPS
bone formation
catechin
EGCG
senolytics
Online Access:https://www.mdpi.com/1422-0067/21/12/4213

Internet

https://www.mdpi.com/1422-0067/21/12/4213

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