A Quantitative Volumetric Micro-Computed Tomography Method to Analyze Lung Tumors in Genetically Engineered Mouse Models

A Quantitative Volumetric Micro-Computed Tomography Method to Analyze Lung Tumors in Genetically Engineered Mouse Models

Two genetically engineered, conditional mouse models of lung tumor formation, K-rasLSL-G12D and K-rasLSL-G12D/p53LSL-R270H, are commonly used to model human lung cancer. Developed by Tyler Jacks and colleagues, these models have been invaluable to study in vivo lung cancer initiation and progressio...

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Bibliographic Details
Main Authors: Brian B. Haines, Kimberly A. Bettano, Melissa Chenard, Raquel S. Sevilla, Christopher Ware, Minilik H. Angagaw, Christopher T. Winkelmann, Christopher Tong, John F. Reilly, Cyrille Sur, Weisheng Zhang
Format: Article
Language:English
Published: Elsevier 2009-01-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558609800870

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http://www.sciencedirect.com/science/article/pii/S1476558609800870

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