Origin of the Genetic Code Is Found at the Transition between a Thioester World of Peptides and the Phosphoester World of Polynucleotides

The early metabolism arising in a Thioester world gave rise to amino acids and their simple peptides. The catalytic activity of these early simple peptides became instrumental in the transition from Thioester World to a Phosphate World. This transition involved the appearances of sugar phosphates, n...

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Bibliographic Details
Main Authors: Hyman Hartman, Temple F. Smith
Format: Article
Language:English
Published: MDPI AG 2019-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/9/3/69