A systematic literature review of evidence-based clinical practice for rare diseases: what are the perceived and real barriers for improving the evidence and how can they be overcome?

A systematic literature review of evidence-based clinical practice for rare diseases: what are the perceived and real barriers for improving the evidence and how can they be overcome?

Abstract Background Evidence-based clinical practice is challenging in all fields, but poses special barriers in the field of rare diseases. The present paper summarises the main barriers faced by clinical research in rare diseases, and highlights opportunities for improvement. Methods Systematic li...

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Bibliographic Details
Main Authors: Ana Rath, Valérie Salamon, Sandra Peixoto, Virginie Hivert, Martine Laville, Berenice Segrestin, Edmund A. M. Neugebauer, Michaela Eikermann, Vittorio Bertele, Silvio Garattini, Jørn Wetterslev, Rita Banzi, Janus C. Jakobsen, Snezana Djurisic, Christine Kubiak, Jacques Demotes-Mainard, Christian Gluud
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Trials
Subjects:
Randomised clinical trials
Evidence-based clinical practice
Evidence-based medicine
Assessment
Specific barriers
Rare diseases
Online Access:http://link.springer.com/article/10.1186/s13063-017-2287-7

Internet

http://link.springer.com/article/10.1186/s13063-017-2287-7

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