Improved Loading of Plasma-Derived Extracellular Vesicles to Encapsulate Antitumor miRNAs

Extracellular vesicles (EVs) carry various molecules involved in intercellular communication and have raised great interest as drug delivery systems. Several engineering methods have been investigated for vesicle loading. Here, we studied the electroporation of EVs isolated from plasma to load antit...

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Bibliographic Details
Main Authors: Margherita Alba Carlotta Pomatto, Benedetta Bussolati, Sergio D’Antico, Sara Ghiotto, Ciro Tetta, Maria Felice Brizzi, Giovanni Camussi
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S232905011930004X