Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

Control of gdhR Expression in Neisseria gonorrhoeae via Autoregulation and a Master Repressor (MtrR) of a Drug Efflux Pump Operon

The MtrCDE efflux pump of Neisseria gonorrhoeae contributes to gonococcal resistance to a number of antibiotics used previously or currently in treatment of gonorrhea, as well as to host-derived antimicrobials that participate in innate defense. Overexpression of the MtrCDE efflux pump increases gon...

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Bibliographic Details
Main Authors: Corinne E. Rouquette-Loughlin, Yaramah M. Zalucki, Vijaya L. Dhulipala, Jacqueline T. Balthazar, Raúl G. Doyle, Robert A. Nicholas, Afrin A. Begum, Erica L. Raterman, Ann E. Jerse, William M. Shafer, Michael S. Gilmore
Format: Article
Language:English
Published: American Society for Microbiology 2017-04-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/2/e00449-17

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http://mbio.asm.org/cgi/content/full/8/2/e00449-17

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